Description
Buy 5F-PB22 Crystal is a designer drug which acts as a cannabinoid agonist. The structure of 5F-PB-22 appears to have been designed with an understanding of structureactivity relationships within the indole class of cannabinoids.
5-fluoro PB-22 (Item No. 14095) is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC (Item Nos. 12068 | ISO60157).1 This product is intended for research and forensic applications.
Pharmacology
5F-PB-22 acts as a full agonist with a binding affinity of 0.468 nM at CB1 and 0.633 nM at CB2cannabinoid receptors.
Chemical and physical data
Formula: C23H21FN2O2
Molar mass: 376.431 g·mol?1
Technical Information of 5F-PB22 Crystal
Formal Name1-(5-fluoropentyl)-8-quinolinyl ester-1H-indole-3-carboxylic acid
CAS Number1400742-41-7
Molecular FormulaC23H21FN2O2
Formula Weight376.4
Purity?98%
FormulationA neat solid
SMILESO=C(OC1=C(N=CC=C2)C2=CC=C1)C3=CN(CCCCCF)C4=C3C=CC=C4
InChi CodeInChI=1S/C23H21FN2O2/c24-13-4-1-5-15-26-16-19(18-10-2-3-11-20(18)26)23(27)28-21-12-6-8-17-9-7-14-25-22(17)21/h2-3,6-12,14,16H,1,4-5,13,15H2
InChi KeyMBOCMBFDYVSGLJ-UHFFFAOYSA-N
WARNING This product is not for human or veterinary use.
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 3 years
See also
AM-2201
JWH-018
QUCHIC
QUPIC
SDB-001
SDB-005
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